2022

Binding of Glycans to the SARS CoV-2 Spike Protein, an Open Question: NMR Data on Binding Site Localization, Affinity, and Selectivity.
Maass T, Ssebyatika G, Brückner M, Breckwoldt L, Krey T, Mallagaray A, Peters T, Frank M, Creutznacher R.
Chemistry. 2022 Dec 20;28(71):e202202614. doi: 10.1002/chem.202202614. Epub 2022 Oct 26. PMID: 36161798 Free PMC article.

BNT162b2-boosted immune responses six months after heterologous or homologous ChAdOx1nCoV-19/BNT162b2 vaccination against COVID-19.
Behrens GMN, Barros-Martins J, Cossmann A, Ramos GM, Stankov MV, Odak I, Dopfer-Jablonka A, Hetzel L, Köhler M, Patzer G, Binz C, Ritter C, Friedrichsen M, Schultze-Florey C, Ravens I, Willenzon S, Bubke A, Ristenpart J, Janssen A, Ssebyatika G, Krähling V, Bernhardt G, Hoffmann M, Pöhlmann S, Krey T, Bošnjak B, Hammerschmidt SI, Förster R.
Nat Commun. 2022 Aug 18;13(1):4872. doi: 10.1038/s41467-022-32527-2, PMID: 35982040

A CMV-induced adaptive human Vδ1+ γδ T cell clone recognizes HLA-DR.
Deseke M, Rampoldi F, Sandrock I, Borst E, Böning H, Ssebyatika GL, Jürgens C, Plückebaum N, Beck M, Hassan A, Tan L, Demera A, Janssen A, Steinberger P, Koenecke C, Viejo-Borbolla A, Messerle M, Krey T, Prinz I.
J Exp Med. 2022 Sep 5;219(9):e20212525. doi: 10.1084/jem.20212525. Epub 2022 Jul 19. PMID: 35852466

Fungal dual-domain LysM effectors undergo chitin-induced intermolecular, and not intramolecular, dimerization.
Tian H, Fiorin GL, Kombrink A, Mesters JR, Thomma BPHJ.
Plant Physiol. 2022 Aug 23;kiac391. doi: 10.1093/plphys/kiac391. PMID: 35997573.

NMR Experiments Provide Insights into Ligand-Binding to the SARS-CoV-2 Spike Protein Receptor-Binding Domain.
Creutznacher R, Maass T, Veselkova B, Ssebyatika G, Krey T, Empting M, Tautz N, Frank M, Kölbel K, Uetrecht C, Peters T.
J Am Chem Soc. 2022 Jul 27;144(29):13060-13065. doi: 10.1021/jacs.2c05603. Epub 2022 Jul 13. PMID: 35830336

Nipah Virus Infection Generates Ordered Structures in Cellulo.
Vázquez CA, Widerspick L, Thuenauer R, Schneider C, Reimer R, Neira P, Olal C, Heung M, Niemetz L, Lawrence P, Kucinskaite-Kodze I, Redecke L, Escudero-Pérez B.
Viruses. 2022 Jul 12;14(7):1523. doi: 10.3390/v14071523. PMID: 35891503 Free PMC article.

A Hepatitis C virus genotype 1b post-transplant isolate with high replication efficiency in cell culture and its adaptation to infectious virus production in vitro and in vivo.
Heuss C, Rothhaar P, Burm R, Lee JY, Ralfs P, Haselmann U, Ströh LJ, Colasanti O, Tran CS, Schäfer N, Schnitzler P, Merle U, Bartenschlager R, Patel AH, Graw F, Krey T, Laketa V, Meuleman P, Lohmann V.
PLoS Pathog. 2022 Jun 28;18(6):e1010472. doi: 10.1371/journal.ppat.1010472. PMID: 35763545

Identification of NS2 determinants stimulating intrinsic HCV NS2 protease activity.
Isken O, Walther T, Wong-Dilworth L, Rehders D, Redecke L, Tautz N.
PLoS Pathog. 2022 Jun 21;18(6):e1010644. doi: 10.1371/journal.ppat.1010644. eCollection 2022 Jun.PMID: 35727826 Free PMC article.

Longitudinal Tracking of Immune Responses in COVID-19 Convalescents Reveals Absence of Neutralization Activity Against Omicron and Staggered Impairment to Other SARS-CoV-2 Variants of Concern.
Odak I, Schultze-Florey CR, Hammerschmidt SI, Ritter C, Willenzon S, Friedrichsen M, Ravens I, Sikora R, Bayir LM, Gutierrez Jauregui R, Bernhardt G, Stankov MV, Cossmann A, Hansen G, Krey T, Cornberg M, Koenecke C, Behrens GMN, Bošnjak B, Förster R.
Front Immunol. 2022 Mar 14;13:863039. doi: 10.3389/fimmu.2022.863039. eCollection 2022. PMID: 35359969.

[Development approaches for vaccines against hepatitis C virus infections].
Bankwitz D, Krey T, Pietschmann T.
Bundesgesundheitsblatt Gesundheitsforschung Gesundheitsschutz. 2022 Feb;65(2):183-191. doi: 10.1007/s00103-021-03477-9. Epub 2022 Jan 11. PMID: 35015104.

Analysis of antibodies from HCV elite neutralizers identifies genetic determinants of broad neutralization.
Weber T, Potthoff J, Bizu S, Labuhn M, Dold L, Schoofs T, Horning M, Ercanoglu MS, Kreer C, Gieselmann L, Vanshylla K, Langhans B, Janicki H, Ströh LJ, Knops E, Nierhoff D, Spengler U, Kaiser R, Bjorkman PJ, Krey T, Bankwitz D, Pfeifer N, Pietschmann T, Flyak AI, Klein F.
Immunity. 2022 Feb 8;55(2):341-354.e7. doi: 10.1016/j.immuni.2021.12.003. Epub 2022 Jan 5. PMID: 34990590.