RTG VISION

(VISualization and imaging of virus infectION)

Projects for the 2^nd cohort:

A1 – AG Bosse (MHH/CSSB Hamburg*): Integrative analysis of herpesvirus protein-protein interaction networks

A2 – AG Kosinski (EMBL/CSSB Hamburg*): Protein-protein interactions determining influenza A virus assembly and infection cycle in host cells

A3 – AG Peters/Behrendt (UzL*/MHH): Studies into binding of attachment factors and neutralizing antibodies to HEV P-dimers with NMR

A4 – AG Uetrecht/Topf (UzL/CSSB Hamburg*): Modelling of N-terminal interfaces and design and functional evaluation of peptides and RNA based structures to interfere with capsid assembly, stability and size

B1 – AG Grünewald (UHH/CSSB Hamburg*): Conformational specific nanobodies against HSV-1 gB that block viral entry

B2 – AG Krey/Vieyres (UzL*): Characterization of SR-B1-mediated lipid transfer

C1 – AG Redecke/Schulz/Brinkmann (UzL*/MHH/TUB): Structural investigation of the HCMV IE2 CTD

C2 – AG Fischer/Pearson (UKE*/UHH): Structural analysis of MCPyV encoded LT Antigen/DNA binding

C3 – AG Tautz/Pearson (UzL*/UHH): Structural and functional analysis of pestiviral NS2pro-NS3pro precursors

C4 – AG Bigalke (UzL*): The role of the non-classical deSUMOylase LUNA from HCMV in viral reactivation from latency

C5 – AG Rosenthal/Topf (BNITM*/CSSB Hamburg): Functional and structural validation of peptide efficacy and binding as well as virtual screening of ultra-large compound libraries to replace effective peptides by compounds

* - Location of PhD